Investigation of melanoma-associated antigen A4 cancer/testis antigen clinical relevance in esophageal squamous cell carcinoma

Conclusion: Because of the significant correlation of MAGEA4 and indices of poor prognosis, the role of this CTA may be confirmed in ESCC aggressiveness and metastasis. Therefore, MAGEA4 may be a promising therapeutic candidate for suppressing ESCC aggressiveness.

Source: Journal of Cancer Research and Therapeutics - September 7, 2018 Category: Cancer & Oncology Authors: Soodabeh Abbasi Sani Mohammad Mahdi Forghanifard Noorieh Sharifi Mahnaz Hashemi Bidokhti Alireza Jian Bagherpoor Mohammad Reza Abbaszadegan Source Type: research