Aluminum Complexes Based on Tridentate Amidoalkoxide NNO-Ligands: Synthesis, Structure, and Properties

Publication date: 15 November 2018Source: Journal of Organometallic Chemistry, Volume 875Author(s): Kirill V. Zaitsev, Valeriy S. Cherepakhin, Alexander Zherebker, Alexey Kononikhin, Eugene Nikolaev, Andrei V. ChurakovAbstractA series of novel NNO-type ligands 12a-17a, LH2, R1N(CH2CH2NHTs)CHR2CR3R4OH (R1 = Bn, R3 = R4 = H; R2 = H (12a), R2= (S)-Ph (13a), R2= (S)-Bn (14a), R2= (S)-i-Bu (15a); R1 = R2= (R)-Me, R3 = H, R4= (S)-Ph (16a); R1 = Bn, R2= (S)-i-Bu, R3 = R4 = Ph (17a)) was obtained; the ligands LH2 feature various degree of substitution, steric bulkiness, and chirality. Treatment of 11a (R1 = Me, R2 = R3 = R4 = H), 12a-17a, and 18a (R1 = Me, R2 = H, R3 = R4 = Ph) with AlMe3 afforded the complexes 11b-18b, [LAlMe]n (n = 1, 2). It was demonstrated that the structure of the ligand determines the monomeric (16b-18b, R3, R4 = Ph) or dimeric (11b-15b, R3 = R4 = H) structure of the complexes. The discussion of the stereochemical consequences caused by dimerization and chirality of the ligands is performed. The molecular structures of dimeric 11b, 12b, 15b, and monomeric 17b were studied by single-crystal X-ray diffraction. Complexes 11b, 12b, 14b, and 17b are active initiators in ring-opening polymerization of l-lactide in the absence of alcohol. Furthermore, 11b-13b, 17b, and 18b demonstrate an outstanding catalytic activity and selectivity in alcoholysis of l-lactide to give (S,S)-methyl lac...
Source: Journal of Organometallic Chemistry - Category: Chemistry Source Type: research

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ConclusionHigh prevalences of underweight and overweight/obesity were identified in ASEAN countries and several correlates were identified which can help to tailor interventions.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Shalaka S. Ramgir and V. G. Abilash*
Source: Indian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research
This study aimed to investigate the risk behaviors of adolescents with T1D and the effect of orthorexic eating behaviors (OEB) on glycemic control (GC). Methods: This cross-sectional study was conducted with 107 adolescents with T1D who were between 13-18 years of age and attended high school. The risk behavior scale (RBS) and orthorexic behavior scale (ORTO-11) were administered to the participants. A high RBS score indicates risky behavior; a low ORTO-11 score suggests a tendency to OEB. At the same time, participants were tested for GC and categorized as optimal GC (HbA1c ≤7%) or poor GC (HbA1c>7%). Result...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
Publication date: Available online 15 November 2019Source: Autoimmunity ReviewsAuthor(s): José María G. Ruiz de Morales, Lluís Puig, Esteban Daudén, Juan D. Cañete, José Luis Pablos, Antonio Olveira Martín, Carlos González Juanatey, Alfredo Adán, Xavier Montalbán, Natalia Borruel, Guillermo Ortí, Esther Holgado Martín, Carolina García-Vidal, Cynthia Vizcaya Morales, Víctor Martín Vázquez, Miguel Ángel González-GayAbstractInterleukin 17 (IL-17) is a proinflammatory cytokine that has been the focus of...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Insomnia can be a disruptive condition that affects your entire life. When you aren’t able to sleep at night, it can negatively impact issues in almost every area of your life and well-being. If you are taking sleeping pills or are thinking about starting to take sleeping pills, make sure you know as much as possible about all the sleeping pill side effects. What Are Sleeping Pills and How Do They Work? Sleeping pills are used to treat insomnia. According to the National Sleep Foundation, insomnia is described as difficulty falling asleep or staying asleep, even when a person has the chance to do so. People with ins...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction to Pharmaceuticals Sleep healthy sleep insomnia sleep aids sleep and chronobiology laboratory sleep deprivation sleep disorder treatment sleep disorders sleep duration sleep habits sleeping sleeping pills sleeplessness Source Type: blogs
What is the Definition of “Opioid”? The definition of opioid is as follows: Opioids are a class of drugs that include the illegal drug heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription, such as oxycodone, hydrocodone, codeine, morphine, and many others. Opioids work by interacting with the opioid receptors on nerve cells in the body and brain. By interacting with these receptors, opioids medications are able to cut off communication between the pain point on the body to the brain. This chemical interaction gives it’s users pain relief that is too great for ov...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction to Pharmaceuticals fentanyl heroin heroin addiction opiate opiate abuse opiate addiction opiates opioid opioids Source Type: blogs
Publication date: March 2020Source: Food Packaging and Shelf Life, Volume 23Author(s): Graziella Pinheiro Bruni, Jean Paulo de Oliveira, Laura G. Gómez-Mascaraque, Maria José Fabra, Vilásia Guimarães Martins, Elessandra da Rosa Zavareze, Amparo López-RubioAbstractIn this work, emulsion electrospinning was used to develop an active internal coating for food packaging applications. Specifically, the antioxidant molecule β-carotene, was encapsulated in a mixture of soy protein isolate (SPI) and polyvinyl alcohol (PVA) which was directly electrospun onto a polyhydroxybutyrate-co-valerate...
Source: Food Packaging and Shelf Life - Category: Food Science Source Type: research
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Source: International Journal of Psychiatry in Clinical Practice - Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research
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Source: The Primary Care Companion for CNS Disorders - Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Hamish A. Watson, Soraya Manaviazar, Hannah G. Steeds, Karl J. Hale O-directed hydrostannation of β-cyclopropyl propargyl alcohol 22 with stannanes and cat. Et3B in THF/H2O or PhMe/MeOH fails to deliver any detectable products of α-stannylvinyl cation capture. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
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