Request for Information (RFI): Current Clinical Management and Assessment Practices in Lung Transplantation
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Condition: Post-Lung Transplantation Bronchiectasis Intervention: Diagnostic Test: Lung ultrasound Sponsor: Mayo Clinic Not yet recruiting
Publication date: Available online 7 October 2020Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Youngmok Park, Nam Eun Kim, Se Hyun Kwak, Moo Suk Park, Su Jin Jeong, Jin Gu Lee, Hyo Chae Paik, Song Yee Kim, Young Ae Kang
LUNG TRANSPLANTATION, either single or bilateral, involves recipient pneumonectomy followed by implantation and reperfusion of the donor lung. Contemporary approaches to lung transplantation require lung isolation to assist recipient pneumonectomy and donor lung implantation.1 Single-lung transplantation requires interruption of ventilation to the side of allograft transplantation, whereas bilateral lung transplantation involves sequential one-lung ventilation (OLV) when performed without mechanical circulatory support.
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Epstein –Barr virus (EBV) is associated with the pathogenesis of a variety of malignancies, most notably lymphomas. Especially in the background of immunodeficiency, such as primary immunodeficiency disorder (P...
Authors: Niroomand A, Lindstedt S PMID: 33021126 [PubMed - as supplied by publisher]
Publication date: Available online 6 October 2020Source: IDCasesAuthor(s): Yanna Ding, Lisa L Steed, Nicholas Batalis
Contributor : Jessica ChangSeries Type : Expression profiling by arrayOrganism : Homo sapiensWe previously developed molecular assessment systems for lung transplant transbronchial biopsies (TBBs) with high surfactant and bronchial mucosal biopsies (3BMBs). Unsupervised machine learning identified T cell-mediated rejection (TCMR) based on expression of validated rejection-associated transcripts (RATs). The relationship to patient outcomes is not known. We aimed to establish whether molecular TCMR in TBBs and 3BMBs has implications for future graft loss. Molecular TCMR scores assigned in all TBBs or high surfactant TBBs agr...
Conclusion: Combination of neoadjuvant therapy and LT is an effective paradigm in treatment of multisystem LCH with severe liver dysfunction. With advances in chemotherapy regimen for multisystem LCH and LT surgery, perspectives on prognosis for LCH children are promising.
AbstractWhile technical considerations in lung transplantation for Kartagener syndrome have been discussed, little information is available about the postoperative morphological changes of the grafted lungs. Herein, we discuss both the technical aspects and postoperative morphological adaptation of the grafted lungs in a case of Kartagener syndrome. A 46-year-old male patient with Kartagener syndrome underwent bilateral cadaveric lung transplantation. The right arterial anastomosis for transplantation of the size-matched grafts required technical elaboration. After the transplantation, we found a free space in the cardiac ...