OncoKids
The OncoKids panel is an amplification-based next-generation sequencing assay designed to detect diagnostic, prognostic, and therapeutic markers across the spectrum of pediatric malignancies, including leukemias, sarcomas, brain tumors, and embryonal tumors. This panel uses low input amounts of DNA (20 ng) and RNA (20 ng) and is compatible with formalin-fixed, paraffin-embedded and frozen tissue, bone marrow, and peripheral blood. The DNA content of this panel covers the full coding regions of 44 cancer predisposition loci, tumor suppressor genes, and oncogenes; hotspots for mutations in 82 genes; and amplification events in 24 genes.
Source: Journal of Molecular Diagnostics - Category: Pathology Authors: Matthew C. Hiemenz, Dejerianne G. Ostrow, Tracy M. Busse, Jonathan Buckley, Dennis T. Maglinte, Moiz Bootwalla, James Done, Jianling Ji, Gordana Raca, Alex Ryutov, Xinjie Xu, Chao Jie Zhen, Jeffrey M. Conroy, Florette K. Hazard, Joshua L. Deignan, Beverly Tags: Regular article Source Type: research
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