Tanzania:Dar Scores High in Fighting Bilharzia, Guinea Worm
[Daily News] TANZANIA has made tremendous strides in eradicating Bilharzia and Guinea Worm Disease, thanks to ambitious school health programme currently undertaken by the government.
This study provides new insight into the landscape-scale epidemiology of a debilitating parasite and can be used to more effectively target ongoing research and possibly eradication and control efforts.
We present an agent-based simulation that models transmission of GW between a shared water source and a large population of dogs. The simulation incorporates various potential factors driving the infections including external factors and two currently used interventions, namely, tethering and larvicide water treatments. By defining and estimating infectivity parameters and seasonality factors, we test the simulation model on scenarios where seasonal patterns of dog infections could be driven by the parasite's life cycle alone or with environmental factors (e.g., temperature and rainfall) that could also affect human or dog...
Abstract The success of the Guinea Worm (GW) Eradication Program over the past three decades has been tempered by the persistence of GW disease in a few African nations and the potential for a future resurgence in cases. Domestic dogs are now a major concern as a disease reservoir as large numbers of cases of canine GW disease are now reported each year, mainly along the Chari River in Chad. As a first step toward the development of a serologic assay for dogs, archived human plasma samples from dracunculiasis-positive donors from Togo were used to select adult female GW antigens for peptide sequencing and cloning....
This report describes in detail the CGWEP surveillance system and explores epidemiological trends in canine Guinea worm cas es during 2015–2018. Our results showed an increased in the number of canine cases detected by the system during the period of interest. The proportion of worms that were contained (i.e., water contamination was prevented) improved significantly over time, from 72.8% in 2015 to 85.7% in 2018 (Mant el-Haenszel chi-square = 253.3, P
Between 2 and 8 April 2020, six suspected human cases of dracunculiasis in Duli village, Gog district, Gambella region, Ethiopia, were reported to WHO.
by Robbie A. McDonald, Jared K. Wilson-Aggarwal, George J. F. Swan, Cecily E. D. Goodwin, Tchonfienet Moundai, Dieudonn é Sankara, Gautam Biswas, James A. Zingeser Global eradication of human Guinea worm disease (dracunculiasis) has been set back by the emergence of infections in animals, particularly domestic dogsCanis familiaris. The ecology and epidemiology of this reservoir is unknown. We tracked dogs using GPS, inferred diets using stable isotope analysis and analysed correlates of infection in Chad, where numbers of Guinea worm infections are greatest. Dogs had small ranges that varied markedly among villages...
Authors: Abstract In the report "Progress Toward Global Eradication of Dracunculiasis - January 2018-June 2019," on page 979, a sentence was omitted from the first paragraph. The paragraph should have read as follows. PMID: 31774742 [PubMed - in process]
This report, based on updated health ministry data, describes progress to eradicate dracunculiasis during January 2018-June 2019 and updates previous reports (2,4,5). With only five countries currently affected by dracunculiasis (Angola, Chad, Ethiopia, Mali, and South Sudan), achievement of eradication is within reach, but it is challenged by civil unrest, insecurity, and lingering epidemiologic and zoologic questions. PMID: 31671082 [PubMed - in process]
This report, based on updated health ministry data, describes progress to eradicate dracunculiasis during January 2018-June 2019 and updates previous reports.
Publication date: 30 March–5 April 2019Source: The Lancet, Volume 393, Issue 10178Author(s): The Lancet