A longitudinal model of human neuronal differentiation for functional investigation of schizophrenia polygenic risk

Common psychiatric disorders are characterized by complex disease architectures with many small genetic effects that contribute and complicate biological understanding of their etiology. There is therefore a pressing need for in vitro experimental systems that allow for interrogation of polygenic psychiatric disease risk to study the underlying biological mechanisms.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Archival Report Source Type: research