Gender identity in patients with 5-alpha reductase deficiency raised as females

5-alpha reductase deficiency (5-ARD) is a rare disorder of sex development. The lack of 5-alpha reductase, an enzyme that converts testosterone into dihydrotestosterone, results in external genitalia that may appear female, or predominantly male, albeit undervirilized, or, more often, ambiguous.

Source: Journal of Pediatric Urology - September 5, 2018 Category: Urology & Nephrology Authors: Rodrigo Lessa Pena Nascimento, Ingrid Michele de Andrade Mesquita, Rhaiana Gondim, Robson Augusto Andrade Cardoso dos Ap óstolos, Maria Betania Toralles, Luciana Barros de Oliveira, Ana Karina Canguçu-Campinho, Ubirajara Barroso Source Type: research