A normative approach to neuromotor control.
A normative approach to neuromotor control. Biol Cybern. 2018 Sep 03;: Authors: Berniker M, Penny S Abstract While we can readily observe and model the dynamics of our limbs, analyzing the neurons that drive movement is not nearly as straightforward. As a result, their role in motor behavior (e.g., forward models, state estimators, controllers, etc.) remains elusive. Computational explanations of electrophysiological data often rely on firing rate models or deterministic spiking models. Yet neither can accurately describe the interactions of neurons that issue spikes, probabilistically. Here we take a normative approach by designing a probabilistic spiking network to implement LQR control for a limb model. We find typical results: cosine tuning curves, population vectors that correlate with reaching directions, low-dimensional oscillatory activity for reaches that have no oscillatory movement, and changes in neuron's tuning curves after force field adaptation. Importantly, while the model is consistent with these empirically derived correlations, we can also analyze it in terms of the known causal mechanism: an LQR controller and the probability distributions of the neurons that encode it. Redesigning the system under a different set of assumptions (e.g. a different controller, or network architecture) would yield a new set of testable predictions. We suggest this normative approach can be a framework for examining the motor system, providing testable li...
Authors: Westwood S Abstract With increasing visibility of older lesbian, gay, bisexual and trans (LGBT) people, there is an urgent need to understand abuse in their lives. This is an under-researched area, which this scoping study (based on a literature review and a small subset of data taken from a larger project) serves to demonstrate. The content of this article formed the basis of a paper presented at a workshop on 'LGBT Elder Abuse' held at Keele University(UK) in 2017, convened and chaired by the author. It considers LGBT elder abuse in terms of polyvictimisation, intersectionality and the abuse of power. Th...
Authors: Lhermite A, Munoz Sastre MT, Sorum PC, Mullet E Abstract The views of laypeople and professionals (nurses, occupational therapists, psychologists, and physicians) on the capacity to make informed decisions of elderly people with depression or dementia were examined. Participants were presented with vignettes created by varying the levels of three factors: (a) the type of decision (e.g., agreeing to surgery), (b) the health problem (e.g., slight depression), and (c) the availability of social support. Through cluster analysis, four different positions were found. Seventeen percent of the participants consid...
CONCLUSION:: Reasons for DRF are multifactorial. Preventive strategies with an emphasis on environmental and behavioural factor modifications are likely to decrease the number of DRF. PMID: 30452300 [PubMed - as supplied by publisher]
Øyvind Gløersen, Thomas Losnegard, Anders Malthe-Sørenssen, Dag Kristian Dysthe, Matthias Gilgien
Thiago Montes Fidale, Hanna Karen Moreira Antunes, Leonardo Roever, Alexandre Gon çalves, Guilherme Morais Puga, Romeu Paulo Martins Silva, Fernando Nazário de Resende, Fernanda Rodrigues de Souza, Beatriz Montes Fidale, Frederico Balbino Lizardo, Elmiro Santos Resende
Mohamed M. Refaey, Dapeng Li
Rong Jiahuan, Su Wenhao, Guan Xiaofan, Shi Wei, Zha Shanjie, He Maolong, Wang Haifeng, Liu Guangxu
Maria Bogdanova, Aleksandra Kostina, Katarina Zihlavnikova Enayati, Arsenii Zabirnyk, Anna Malashicheva, K åre-Olav Stensløkken, Gareth John Sullivan, Mari-Liis Kaljusto, John-Peder Escobar Kvitting, Anna Kostareva, Jarle Vaage, Arkady Rutkovskiy
Isabella dos Santos Alves, Carlos Augusto Kalva-Filho, Rodrigo Aquino, Leonardo Travitzki, Alessandro Tosim, Marcelo Papoti, M árcio Pereira Morato
Ma ëlle Wirth, Aurélie Naud, Emmanuelle Schmitt, Isabelle Clerc-Urmès, Jean-Michel Hascoët