Imaging in Lyme neuroborreliosis
This article can educate those engaged in imaging of the nervous system and serve as a comprehensive tool in clinical cases.Key Points•Diagnostic criteria for LNB emphasise exclusion of an alternative cause to the clinical symptoms.•MRI makes a crucial contribution in the diagnosis and follow-up of LNB.•MRI may have normal findings, or show neuritis, meningitis, myelitis, encephalitis or vasculitis.•White matter lesions are not a prominent feature of LNB.
Publication date: Available online 10 July 2020Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Ricardo Becker Feijo, Juarez Cunha
Publication date: Available online 11 July 2020Source: Autoimmunity ReviewsAuthor(s): Romain Paule, Marguerite Vignon, Alexis Régent, Jonathan London, Pascal Cohen, Claire Le Jeunne, Luc Mouthon, Didier Bouscary, Jérôme Tamburini, Benjamin Terrier, the French Vasculitis Study Group
Conclusion: Pediatric endogenous bacterial endophthalmitis is a rare but potentially devastating infection which is often misdiagnosed. Moreover, we want to highlight the importance of an adequate clinical suspicion in cases of H. influenzae to prevent the serious complications seen in this report. PMID: 32644889 [PubMed - as supplied by publisher]
Publication date: 11–17 July 2020Source: The Lancet, Volume 396, Issue 10244Author(s): Daniel Pan, Leslie R Bridges, John du Parcq, Ula Mahadeva, Shantanu Roy, Ibne K M Ali, Catherine A Cosgrove, Peter L Chiodini, Liqun Zhang
Authors: Hatano K, Katsuse K, Suzuki T, Hashida H PMID: 32641655 [PubMed - as supplied by publisher]
ConclusionThis is a rare case of a giant chronic calcified subdural empyema with no known preceding history of trauma or infection.
AbstractFatty acid oxidation disorders (FAOD) are a group of rare, autosomal recessive, metabolic disorders caused by variants of the genes for the enzymes and proteins involved in the transport and metabolism of fatty acids in the mitochondria. Those affected by FAOD are unable to convert fatty acids into tricarboxylic acid cycle intermediates such as acetyl-coenzyme A, resulting in decreased adenosine triphosphate and glucose for use as energy in a variety of high-energy –requiring organ systems. Signs and symptoms may manifest in infants but often also appear in adolescents or adults during times of increased meta...
AbstractThe aim of this study was to improve flavivirus field monitoring in Brazil using a reliable probe-based RT-qPCR assay. Standard flavivirus strains were employed to evaluate the performance of the assay, and its applicability was evaluated using 235 stored pools ofCulicidae samples collected between 1993 and 1997 and in 2016. Flavivirus species were identified by sequencing. Sixteen (6.8%) samples tested positive: Ilheus virus, Iguape virus, and Saint Louis encephalitis virus were identified in historical specimens from 1993-1994, while insect-specific flaviviruses were detected in the samples from 2016. This approa...
Publication date: Available online 10 July 2020Source: Ticks and Tick-borne DiseasesAuthor(s): Alaa M. Al-Khafaji, Lesley Bell-Sakyi, Gerardo Fracasso, Lisa Luu, Dieter Heylen, Erik Matthysen, José A. Oteo, Ana M. Palomar
Publication date: Available online 10 July 2020Source: Ticks and Tick-borne DiseasesAuthor(s): Jessica D.M. Valente, Patrícia W. Silva, Márcia Arzua, Darci M. Barros-Battesti, Thiago F. Martins, Aparecida M. Silva, Thállitha S.W.J. Vieira, Marcelo B. Labruna, Rafael F.C. Vieira