Imaging in Lyme neuroborreliosis
This article can educate those engaged in imaging of the nervous system and serve as a comprehensive tool in clinical cases.Key Points•Diagnostic criteria for LNB emphasise exclusion of an alternative cause to the clinical symptoms.•MRI makes a crucial contribution in the diagnosis and follow-up of LNB.•MRI may have normal findings, or show neuritis, meningitis, myelitis, encephalitis or vasculitis.•White matter lesions are not a prominent feature of LNB.
In conclusion, resolution of CIPN requires in vivo education of CD8+ T cells by exposure to cisplatin. Future studies should examine whether ex vivo CD8+ T cell education could be applied as a therapeutic strategy for treating or preventing CIPN in patients.
Conclusion: 16 of 19 studies treated by CHM granules only showed positive result in 7 diseases and negative result in 1 disease. 17 of 21 studies treated by combination therapy against conventional therapy showed positive result in 6 diseases and negative result in 3 diseases. However, both the absolute and relative effectiveness of CHM formula granules compared with placebo need to be considered clinically. PMID: 31110552 [PubMed]
This study represents the first description of B. venatorum and B. bigemina in roe deer from Spain.Graphical abstract
The family name of the co-author of the article mentioned above was incorrectly spelled. The correct name should have been“Veena S. Katikineni”instead of“Veena Katikeneni”. The original article has been corrected.
PMID: 31109503 [PubMed - in process]
Publication date: Available online 22 May 2019Source: BiologicalsAuthor(s): Niraj Shende, Abhijeet Karale, Preeti Marathe, Sourish Chakraborty, Asha D. Mallya, Rajeev M. DhereAbstractSodium dodecyl sulfate (SDS) is a commonly used surfactant in protein solubilization and also during the polysaccharide purification. A GC-MS method has been developed to quantitate residual SDS in meningococcal polysaccharide serogroups A,C,W,Y and X circumventing the need of spectroscopic assays and HPLC based methods which are either unstable or requires the confirmation by MS. The developed method is based on quantitative conversion of SDS...
Authors: Mahdi AS, Al-Khalili SM, Chung CC, Molai M, Ibrahim H, Eskild P, Khamis F, Nenad P Abstract Scrub typhus is a potentially fatal rickettsial infection caused by Orientia tsutsugamushi. It is an obligate intracellular Gram-negative bacterium transmitted by the bite of infected chigger larva. The disease is distributed from Asia to the Pacific islands, and this region is known as the Tsutsugamushi Triangle. A 28-year-old man was admitted to the Royal Hospital with a four-day history of fever, headache, rigors, anorexia, and a nonspecific macular rash. Clinical presentation, laboratory results as well as epide...
Conditions: Gastrointestinal Cancer; Colorectal Cancer Interventions: Diagnostic Test: Ultrasound - Serial and Tibial Nerve; Procedure: Skin Biopsy; Other: Abbreviated Neurologic Exam; Other: Blood draw; Diagnostic Test: Nerve Conduction Study; Other: QLQ-CIPN20 Questionnaire Administration Sponsors: Wake Forest University Health Sciences; National Cancer Institute (NCI) Not yet recruiting