Children ’s Mercy researcher receives $5M renewal for kidney disease study

Children ’s Mercy researcher Dr. Bradley Warady received another $5 million to continue a long-running study of chronic kidney disease in children. On Aug. 24, the National Institutes of Health (NIH) awarded the grant to Warady, director of pediatric nephrology, who has led the study at Children's Mercy i n conjunction with the Children’s Hospital of Philadelphia for 15 years. The observational study, called CKiD, has been running since 2003 and includes 54 centers. It’s intended to track…
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Conclusions: Alpha-tocopherol pre-treatment is associated with reduction of incidence of CIN. Its administration deserves to be further explored as a simple and inexpensive tool for CIN prevention. PMID: 31017554 [PubMed - as supplied by publisher]
Source: International Journal for Vitamin and Nutrition Research - Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
Crohn’s Disease in Clinical Remission Is Marked by Systemic Oxidative Stress Arno R. Bourgonje1, Julius Z. H. von Martels1, Marian L. C. Bulthuis2, Marco van Londen3, Klaas Nico Faber1, Gerard Dijkstra1† and Harry van Goor2*† 1Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands 2Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands 3Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Gro...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
ConclusionsCases of renal tubular acidosis should be carefully evaluated to prevent adverse complications, uncover a potentially treatable condition, and prevent the progression to chronic kidney disease. Repeated episodes of unexplained hypokalemia could be an important clue for diagnosis.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Publication date: Available online 24 April 2019Source: Veterinary MicrobiologyAuthor(s): Angelica Stranieri, Stefania Lauzi, Annachiara Dallari, Maria Elena Gelain, Federico Bonsembiante, Silvia Ferro, Saverio PaltrinieriAbstractFeline morbillivirus (FeMV) is an emerging virus that was first described in Hong Kong in 2012. Several reports suggested the epidemiological association of FeMV infection with chronic kidney disease (CKD) in cats. The aim of this study was to investigate the presence and the genetic diversity of FeMV as well as the relationship between FeMV infection and CKD in cats from Northern Italy. Urine (n&...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
DiscussionThe mortality in the medium and long term of these patients was very high, much higher than that observed in patients undergoing the same procedure not on dialysis. The review is exceptional, and the functional evaluation of the few living patients shows poor clinical–radiological results.ResumenObjetivoEvaluar la incidencia de mortalidad, revisión y valoración funcional en la artroplastia de cadera en pacientes dializados en Uruguay.MétodosSe realizó un estudio observacional analítico de una cohorte histórica de artroplastias de cadera en pacientes con enfermedad r...
Source: Revista Espanola de Cirugia Ortopedica y Traumatologia - Category: Orthopaedics Source Type: research
Chronic kidney disease (CKD) is a public health problem worldwide, and proteinuria is a well-established marker of disease progression in CKD patients. Propolis, a natural resin produced by bees from plant mat...
Source: BMC Nephrology - Category: Urology & Nephrology Authors: Tags: Research article Source Type: research
Sepsis-associated acute kidney injury (S-AKI) significantly worsens patient prognosis, and recent evidence suggests that the injury process begins early and may be sustained by therapies used to treat the sepsis (e.g., fluids resuscitation, antibiotics). While efforts to develop less-injurious treatments are making progress, some degree of secondary injury is to be expected. So too is the inevitable nature of organ injury, which is often present at the time the patient seeks medical attention. We recently found that most patients presenting with septic shock and developing AKI had evidence of kidney damage at the time of, ...
Source: Nephron - Category: Urology & Nephrology Source Type: research
Conclusion: CKD patients have a high morbidity of ESS, mainly low T3 syndrome. Anemia, inflammation, and malnutrition may contribute to ESS in CKD.Kidney Blood Press Res
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s):
Source: Advances in Chronic Kidney Disease - Category: Urology & Nephrology Source Type: research
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s):
Source: Advances in Chronic Kidney Disease - Category: Urology & Nephrology Source Type: research
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