Miracor Medical closes $35m Series D

Miracor Medical Systems said today it raised $34.6 million (EU €30 million) Series D round of financing to help support the development and commercialization of its PiCSO Impulse System. The round was led by Ming Capital and co-led by a strategic investor, the Belgium-based company said. The round was also joined by newly invested Belgian investment fund Quest for Growth and existing investors Ming Capital, SFPI and Meusinvest. The company’s PiCSO therapy is designed to be used during stenting procedures for patients affected by acute myocardial infarcts to improve pressure in the coronary venous system to improve microcirculatory flow and improve perfusion in the infarcted area. Data from a recent trial of the PiCSO device, presented at the EuroPCR 2018 conference, indicates that use of the PiCSO impulse system is associated with early improvement of coronary microvascular function, and that therapy with the system results in significantly lower Index of Microcirculatory Resistance scores at 24 to 48 hours compared to control treatments. “These clinical results are very encouraging. The additional funds enable us to validate the technology in new clinical studies including a randomized clinical trial to start this year in Europe, and launch the PiCSO therapy to help patients,“ CEO Olivier Delporte said in a press release. In January, Miracor Medical said that it closed a $30.2 million (EU €25 million) round of funding as part of Series D...
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News Cardiovascular Funding Roundup Miracor Source Type: news

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Authors: Ando S, Tsutsui S, Miyoshi K, Sato S, Yanagihara W, Setta K, Chiba T, Fujiwara S, Kobayashi M, Yoshida K, Kubo Y, Ogasawara K Abstract OBJECTIVE: Adult patients with ischemic moyamoya disease (MMD) who receive treatment with antiplatelet drugs reportedly show improvements in neuropsychological test scores after around 2 years. The purpose of the present study subanalyzing the same patient cohort used in a previous study was to determine which antiplatelet drug, clopidogrel or cilostazol, results in better improvement of cognitive function among non-surgical adult patients showing ischemic MMD without ...
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
A peripheral perfusion resuscitation strategy was not superior to the standard lactate-level testing currently used in patients with early septic shock in the five-country ANDROMEDA-SHOCK trial.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Critical Care News Source Type: news
Conditions:   Left Hemispheric Stroke, Subacute Phase;   Left Hemispheric Stroke, Chronic Phase Intervention:   Diagnostic Test: Perfusion functional Magnetic Resonance Imaging (perfusion fMRI) Sponsors:   Kessler Foundation;   Rutgers University;   National Center for Medical Rehabilitation Research (NCMRR) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Peripheral Perfusion Intervention:   Procedure: Radial artery cannulation Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Left Hemispheric Stroke, Subacute Phase;   Left Hemispheric Stroke, Chronic Phase Intervention:   Diagnostic Test: Perfusion functional Magnetic Resonance Imaging (perfusion fMRI) Sponsors:   Kessler Foundation;   Rutgers University;   National Center for Medical Rehabilitation Research (NCMRR) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Peripheral Perfusion Intervention:   Procedure: Radial artery cannulation Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Introduction: TRAP syndrome (Twin Reversed Arterial Perfusion) is a rare complication of monochorionic twins with an incidence of 1:100 in monozygotic twins and 1:35,000 in all pregnancies. One of the twins lacks cardiac function (acardiac) but grows slowly receiving blood from the healthy twin through arterio-arterial anastomoses. The risk of death for the fetus-donor is high (50%) due to cardiac insufficiency, and in 33% demise happens
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Movies – Extra Case Reports – Obstetrics and Prenatal Diagnosis Source Type: research
Introduction: Sustained suppression of plasma viral load is the key to preventing vertical transmission from HIV-infected women to their infants. Current guidelines recommend antiretroviral therapy for all HIV infected pregnant women, starting before the pregnancy. However, the choice of which antiretroviral medications to be used must take into account the tolerance for the developing fetus, in view of the placental transfer of the drugs used.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Session 16 – Obstetrics: High risk pregnancy Source Type: research
Introduction: Magnetic resonance imaging with dynamic contrast enhancement (DCE-MRI) allows quantitative assessment of perfusion kinetics. Intensity of signal is associated with vascular tissue density and blood flow velocity.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Multidisciplinary 2 – Gynaecology Source Type: research
Tissue engineering and regenerative medicine looks at improving or restoring biological tissue function in humans and animals. We consider optimising neotissue growth in a three-dimensional scaffold during dynamic perfusion bioreactor culture, in the context of bone tissue engineering. The goal is to choose design variables that optimise two conflicting objectives, first, maximising neotissue growth and, second, minimising operating cost. We make novel extensions to Bayesian multiobjective optimisation in the case of one analytical objective function and one black-box, i.e. simulation based and objective function. The anal...
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
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