Prepare for Impact: Developing Collective Workload Codes to Quantify Advanced Practice Radiation Therapy Clinical Activities

Key motivations for the development of the Clinical Specialist Radiation Therapist (CSRT) role in Ontario were to improve the quality of cancer care and maximize system efficiency. Quantifying the value or impact of each role is integral to sustainability especially in times of fiscal restraint. Our institution currently has 4 distinct CSRT roles in: brachytherapy, stereotactic body radiation therapy (SBRT), non-melanoma skin cancer and brain radiosurgery. In order to assess the value afforded by the clinical practice of each role, electronic workload codes were created to capture patient related encounters, which can subsequently be used to quantify impact in terms of quantity measures (e.g.
Source: Journal of Medical Imaging and Radiation Sciences - Category: Radiology Authors: Source Type: research

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AbstractImmunotherapy is now widely established as a potent and effective treatment option across several types of cancer. However, there is increasing recognition that not all patients respond to immunotherapy, focusing attention on the immune contexture of the tumor microenvironment (TME), drivers of the immune response and mechanisms of tumor resistance to immunity. The development of novel immunotherapeutics and their use in combination with checkpoint inhibitors and other standard of care and novel treatment modalities is an area of particular attention across several tumor types, including melanoma, lung, ovarian, br...
Source: Journal for Immunotherapy of Cancer - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: Although our meta-analysis showed statistically significant increased risks of either cancer incidence or mortality of certain cancers in association with firefighting, a number of important limitations of the underlying studies exist, which, precluded our ability to arrive at definitive conclusions regarding causation. PMID: 31759344 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
This article, unfortunately paywalled, is interesting to note as a mark of the now increasingly energetic expansion of commercial efforts in longevity science. David Sinclair has been building a private equity company to work in many areas relevant to this present generation of commercial longevity science; while I'm not sold on his primary research interests as the basis for meaningful treatments for aging, he is diversifying considerably here, including into senolytics, the clearance of senescent cells demonstrated to produce rejuvenation in animal studies. This sort of approach to business mixes aspects of investing and...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Brown L, David J, Skopit S Abstract Basal cell carcinoma (BCC) is a common skin malignancy comprising 80% of non-melanoma skin cancers.1 Over 2.8 million cases are estimated to be diagnosed in the United States alone each year. Advanced BCCs are comprised of BCCs that have metastasized to local or distant lymph nodes or organs, or locally invasive BCCs that are extensive and infiltrate vital structures such as eyes, nose, or brain. Advanced BCC tumors represent roughly 1-10% of BCCs today. Two severe case presentations and treatment options will be discussed in this case report series and review. J Drugs D...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
[Image from unsplash.com]From Hologic’s new product launch to CapsoVision gettting CE Mark approval, here are seven medtech stories we missed this week but thought were still worth mentioning. 1. Hologic launches new MyoSure device Hologic announced in a Nov. 1 press release that it has launched its MyoSure Manual Device in the U.S. The device is designed to help doctors resect and remove intrauterine tissue easily in an office setting if used with the MyoSure hysteroscope. 2. IntraFuse wins FDA clearance for FlexThread fibula pin IntraFuse has received FDA 510(k) clearance for its FlexThread Fibula Pin System, ...
Source: Mass Device - Category: Medical Devices Authors: Tags: 510(k) Endoscopic / Arthroscopic Oncology Orthopedics Pain Management Regulatory/Compliance Surgical Ultrasound Women's Health brhmedical CapsoVision Helomics Hologic Inc. IntraFuse MedTech Sensus Healthcare LLC Skyline Med Source Type: news
Author Affiliations open 1 McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Canada 2 Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain 3 Universitat Pompeu Fabra (UPF), Barcelona, Spain 4 CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain 5 School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada 6 Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA 7 Department of Economics, Brigham Young University, Provo, Utah, USA 8 Population Studies Division, Health Canada, Ottawa, Cana...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Conclusions: There is considerable variation in radon and UV exposure across Switzerland. Our study suggests both are relevant risk factors for skin cancer mortality. A better understanding of the role of the UV radiation and radon exposure is of high public health relevance. https://doi.org/10.1289/EHP825 Received: 19 July 2016 Revised: 28 October 2016 Accepted: 15 November 2016 Published: 16 June 2017 Address correspondence to D. Vienneau, Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051, Basel, Switzerland. Telephone: 41 (0) 61-284-8398. E-mail: dan...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
This study was conducted to assess the prevalence of cancer in the elderly covered by the Islamic Republic of Iran Broadcasting (IRIB) insurance program and to obtain suitable programs for cancer screening and early detection, increase patient survival, improve elderly care and to reclaim the cost of treatment in comparison to the national and international statistics. This is a cross-sectional study conducted on all elderly patients diagnosed with malignancy based on their pathology reports. In this study, of the total 75,500 patients covered by IRIB insurance, 17.2% belonged to the elderly group, males accounting for 53....
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
Nucleotide excision repair (NER) is the most versatile DNA repair pathway to remove DNA damage caused by UV radiation and many chemical carcinogens in the environment. NER is essential for suppressing tumorigenesis in the skin, lungs and brain. Loss of function of NER factors in humans can lead to the Xeroderma Pigmentosum (XP) syndrome, characterized by 2,000-10,000 fold increased risk of carcinogenesis at a very young age, especially for non-melanoma skin cancer and melanoma. Although the core factors in the NER pathway are identified, regulation of the NER pathway remains poorly understood.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Photobiology Source Type: research
Abstract: Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs) in combination with lymphodepletion and high-dose interleukin 2 has shown reproducible objective response rates of approximately 50% in patients with highly advanced, refractory metastatic melanoma. As confirmed by different clinical centers, TIL ACT can yield durable responses especially in patients with complete regression, who are mostly disease-free many years after treatment, suggesting the possibility of cure. Most TIL ACT trials have been conducted as salvage therapy for patients with multiple metastases, frequently in visceral organs a...
Source: The Cancer Journal - Category: Cancer & Oncology Tags: Reviews Source Type: research
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