Crystal structure of the post-fusion core of the Human coronavirus 229E spike protein at 1.86   Å resolution

This study adds to the structural profiling of HCoVs to aid in the structure-based design of pan-coronavirus small molecules or peptides to inhibit viral fusion.

Source: Acta Crystallographica Section D - September 3, 2018 Category: Biochemistry Authors: Yan, L. Meng, B. Xiang, J. Wilson, I.A. Yang, B. Tags: coronavirus HCoV-229E spike protein post-fusion core X-ray structure SARS MERS research papers Source Type: research