HEALTH NOTES: Egg scientists crack hair loss

An egg a day may keep hair loss at bay, according to dermatologists in Japan. A series of studies, in which human hair follicles were implanted into mice, found that egg yolk stimulated growth.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Missense mutations in the Gasdermin-A3 (Gsdma3) gene are associated with skin inflammation and hair loss in mice. However, the physiological function of Gsdma3 remains unclear. Here we reported that mice carrying the Gsdma3 Y344H mutation that encodes a presumptive activated form of Gsdma3, show increased heat production along with lower body fat percentages. Detailed analysis indicated that this metabolic phenotype is mediated by serum interleukin-6 –induced up-regulation of thermogenesis in brown adipose tissue.
Source: American Journal of Pathology - Category: Pathology Authors: Tags: Regular article Source Type: research
Authors: AtaƟ H, Gönül M, Öztürk Y, Kavutçu M Abstract Background/aim: Results show that oxidative stress is a pathophysiologic factor for alopecia areata (AA); however, the markers used can be confounding. Thus, we aimed to investigate the role of oxidative stress in the pathogenesis of AA through an evaluation of ischemia-modified albumin (IMA); other markers of the oxidant/antioxidant system, such as SOD, CAT, GSH-ST, and MDA; and contributing clinical risk factors. Materials and methods: The usefulness of IMA as a new marker for oxidative stress was compared with that of other ma...
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
Skin toxicity is a common problem not only when treating breast cancer but in all cancer types. Visible on the surface, these side effects come not just with burdening symptoms but also with stigmatization. With increasing diversity in therapeutic options, dermatologic side effects are also becoming increasingly complex and more challenging for the clinician. We reviewed the most common dermatologic side effects of current anticancer therapy, including toxicity induced by chemotherapy, targeted therapy, and immunotherapy. In particular, we focus on xerosis and pruritus, (acneiform) exanthema, hand-foot syndrome, nail toxic...
Source: Breast Care - Category: Cancer & Oncology Source Type: research
This article presents what is known about trichotillomania and the evidence for a variety of treatment interventions. PMID: 30745687 [PubMed]
Source: Indian Journal of Psychiatry - Category: Psychiatry Tags: Indian J Psychiatry Source Type: research
-- Alopecia areata is a form of hair loss that's triggered by your immune system mistakenly viewing hair follicles as threats to your health. This can trigger patchy hair loss on the head, complete hair loss on the head or the loss of body hair, the...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
ConclusionsThe study highlights the differences in utility between base health states and the significant impact of treatment-related AEs on the HRQL of patients with mHSPC. These findings underline the importance of accounting for impaired HRQL when assessing treatments for mHSPC.
Source: Quality of Life Research - Category: Health Management Source Type: research
Abstract BACKGROUND: Selective Serotonin Reuptake Inhibitors (SSRIs) are the first-line treatments for various psychiatric disorders. SSRIs offer improved side effect profile compared to older treatments, which improve patient adherence and quality of life. CASE REPORT: Here we discuss a case of an uncommon, but distressing side effect of citalopram. A 76-year old woman was referred to the psychiatry clinic for bizarre behavior. Patient was diagnosed with behavioral variant frontotemporal dementia, and was started on citalopram 20 mg and aripiprazole 5 mg daily. At 3.5 months the patient complained of diffuse...
Source: Current Drug Safety - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Saf Source Type: research
AbstractPurpose of reviewTo give an overview on the current evidence for stereotactic radiosurgery of brain metastases with a special focus on multiple brain metastases.Recent findingsWhile the use of stereotactic radiosurgery in patients with limited brain metastases has been clearly defined, its role in patients with multiple lesions (>  4) is still a matter of controversy. Whole-brain radiation therapy (WBRT) has been the standard treatment approach for patients with multiple brain lesions and is still the most commonly used treatment approach worldwide. Although distant brain failure is improved by WBRT, the ...
Source: Current Treatment Options in Neurology - Category: Neurology Source Type: research
Chemotherapy-induced alopecia has been well documented as a cause of distress to patients undergoing cancer treatment. Almost all traditional chemotherapeutic agents cause severe alopecia. Despite advances in ...
Source: BMC Cancer - Category: Cancer & Oncology Authors: Tags: Research article Source Type: research
This article aims at exposing the most prevalent among abuses in trichological practice due to autistic-undisciplined thinking, specifically: iron supplementation, antiandrogenic treatment, and individualized cell-based therapy in female androgenetic alopecia, treatment of folliculitis decalvans with retinoids, and the value of nutritional therapies.
Source: International Journal of Trichology - Category: Dermatology Authors: Source Type: research
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