Atypical Femur Fractures - Review of epidemiology, relationship to bisphosphonates, prevention and clinical management.

In conclusion, AFFs can be devastating events but even under the most pessimistic assumptions, the benefit to risk ratio is highly positive for BPs particularly over the first 3-5 years of use. As our understanding of AFF increases, it is becoming increasingly possible to maximize BP benefits while minimizing AFF risk. PMID: 30169557 [PubMed - as supplied by publisher]
Source: Endocrine Reviews - Category: Endocrinology Tags: Endocr Rev Source Type: research