GSE108924 Transcriptome analysis of wild-type and maternal ybx1 mutant zebrafish embryos during early development

Contributors : Jiawei Sun ; Anming MengSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioTo study the function of zebrafish Ybx1 during early embryogenesis, we generated maternal ybx1 (Mybx1) mutant using CRISPR/Cas9 and report the transcriptome-wide changes in comparison to wild-type (WT) embryos. Our analysis reveals a dramatic loss of maternal mRNA decay and zygotic genome activation in Mybx1 embryos during maternal-to-zygotic transition.

Source: GEO: Gene Expression Omnibus - September 1, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Danio rerio Source Type: research