Antihyperglycemic medications for cardiovascular disease risk reduction.

Antihyperglycemic medications for cardiovascular disease risk reduction.
Am J Manag Care. 2018 Aug;24(13 Suppl):S273-S278
Authors: Goldman JD
Abstract
In recognition of the substantial prevalence of cardiovascular disease-related comorbidities among patients with diabetes and the potential for some agents to increase this risk, evaluation of cardiovascular outcomes is now a standard component of late-stage clinical trials involving antihyperglycemic agents. While most agents are evaluated in noninferiority trials to establish a lack of cardiovascular-related harm, a few agents have shown significant reductions in cardiovascular-related outcomes, including mortality.
PMID: 30160394 [PubMed - in process]

Source: The American Journal of Managed Care - August 1, 2018 Category: Health Management Authors: Goldman JD Tags: Am J Manag Care Source Type: research