Epidemiology and molecular characterization of colistin-resistant Klebsiella pneumoniae isolates from immunocompromised patients in Tunisia

Klebsiella pneumoniae is an important pathogen involved in nosocomial outbreaks. Increased resistance to multiple antimicrobial agents including β-lactams, aminoglycosides and quinolones is associated to this microorganism. Outbreaks of extended spectrum β-lactamases (ESBL)-producing K. pneumoniae have been extensively reported worldwide [1]. Thus, carbapenems were used for infections caused by ESBL-producing pathogens leading to the emerg ence of resistant carbapenem K. pneumoniae [2]. Consequently, carbapenem resistance emerged and become a significant problem in terms of public health and clinical outcome [3].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Tags: Short Communication Source Type: research