Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study.

Conclusion: Increase serum TGs, UA and GL concentrations were higher in the middle-aged individuals compared with their children in families independently of their lifespan. The serum adiponectin concentration was the highest in the oldest old individuals implying beneficial influence on lifespan. Independently of family's lifespan history, the youngest individuals with CETPB2B2 genotype, compared with individuals with CETPB1B1 genotypes, had lower serum CETP concentrations. The knowledge of the unfavourable gene(s)influencing human lifespan may be helpful in encouraging individuals to follow healthier lifestyle habits and better control their high-risk biomarkers. PMID: 30159092 [PubMed]
Source: Open Cardiovascular Medicine Journal - Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research