Irisin levels in lmna-associated partial lipodystrophies.

CONCLUSION: -: Circulating irisin is similarly increased in FPLD2 and OND patients, who are characterized by higher lean body mass regardless of their clearly different fat mass. However, irisin/leptin ratios, strikingly higher in FPLD2 than in OND patients, could help to make the diagnosis and prompt genetic testing in clinically atypical cases.
PMID: 30165155 [PubMed - as supplied by publisher]

Source: Diabetes and Metabolism - August 27, 2018 Category: Endocrinology Authors: Bensmaïne F, Benomar K, Espiard S, Vahe C, LE Mapihan K, Lion G, Lemdani M, Chazard E, Ernst O, Vigouroux C, Pigny P, Marie-Christine V Tags: Diabetes Metab Source Type: research