Lifestyles of a Toxic Twosome: A Novel Tau Strain Induced by α-Synuclein Oligomers

One of the key dicta of disease diagnosis learned in medical school is Occam ’s razor: do not posit multiple causes without necessity. Neurological syndromic diagnoses developed in the 19th century were based on shared signs, symptoms, temporal courses, and gross and microscopic post mortem findings. With the evolution of biophysical, genetic, and imaging approaches to neu rodegeneration, however, it has become increasingly clear that nosological distinctions derived from observations of the 19th and early 20th centuries are artificial.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Commentary Source Type: research