[Determination of Hexazinone and Its Major Metabolites in Livestock Products by LC-MS/MS].

[Determination of Hexazinone and Its Major Metabolites in Livestock Products by LC-MS/MS]. Shokuhin Eiseigaku Zasshi. 2018;59(4):167-173 Authors: Kubota A, Okabe R, Kakimoto Y, Nemoto S, Aoyagi M Abstract A method for the determination of hexazinone and three metabolites (hexazinone metabolite B, hexazinone metabolite C, hexazinone metabolite F) in livestock products by LC-MS/MS was developed. Hexazinone and the three metabolites were extracted from a sample with acetonitrile in the presence of n-hexane, and lipid was removed by acetonitrile/n-hexane partition. The acetonitrile extract was cleaned up using a SAX/PSA cartridge column. Average recoveries (n=5) of hexazinone and the three metabolites from cattle meat, fat, liver and milk spiked at the maximum residue limits (MRLs) or at 0.0025 mg/kg ranged from 85.6 to 96.0%, and the relative standard deviations ranged from 0.8 to 4.9%. PMID: 30158395 [PubMed - in process]
Source: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan - Category: Food Science Tags: Shokuhin Eiseigaku Zasshi Source Type: research