Medical News Today: Stroke significantly increases the risk of dementia

In the largest analysis of its type to date, researchers conclude that stroke significantly increases the risk of developing dementia in older age.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Stroke Source Type: news

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It is well known that hypertension, raised blood pressure, results in greater risk of a range of age-related conditions, particularly cognitive decline and dementia. The mechanisms of interest include damage to the blood-brain barrier, allowing unwanted molecules and cells into the brain, where they can spur chronic inflammation, and rupture of small blood vessels in the brain, resulting in microbleeds that are effectively tiny strokes, destroying small regions of tissue. Over time, this all adds up, and is why even methods that force a lowering of blood pressure without addressing the underlying causes of hypertension can...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Authors: Wanleenuwat P, Iwanowski P, Kozubski W Abstract Alzheimer's disease (AD) is the most common form of dementia manifesting as alterations in cognitive abilities, behavior and deterioration in memory which is progressive, leading to gradual worsening of symptoms. Major pathological features of AD are accumulations of neuronal amyloid plaques and neurofibrillary tangles, with early lesions appearing primarily in the hippocampus, the area of the brain involved in memory and learning. Cardiovascular related risk factors are believed to play a crucial role in disease development and the acceleration of cognitive ...
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Conclusion: Neurological disorders are common in HIV in Africa and the main CNS opportunistic infections result in high  mortality rates. Strategies aimed at reducing their high burden, morbidity and mortality include early HIV diagnosis and anti-retroviral therapy (ART), screening and chemoprophylaxis of main opportunistic infections, improved clinical diagnosis and management and programme strengthening.Keywords: Neurological disorders, HIV, Africa, opportunistic infections, direct HIV infection and inflammatory disorders.
Source: African Health Sciences - Category: African Health Source Type: research
CONCLUSIONS: Physicians had a lower prevalence for dementia than the general population. The prevalence for dementia in specific subgroups of physicians was higher, which needs to be clarified by further studies. PMID: 31428999 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - Category: Geriatrics Authors: Tags: Aging Clin Exp Res Source Type: research
Abstract Small-vessel diseases (SVDs) of the brain are involved in about one-fourth of ischemic strokes and a vast majority of intracerebral hemorrhages and are responsible for nearly half of dementia cases in the elderly. SVDs are a heavy burden for society, a burden that is expected to increase further in the absence of significant therapeutic advances, given the aging population. Here, we provide a critical appraisal of currently available therapeutic approaches for nonamyloid sporadic SVDs that are largely based on targeting modifiable risk factors. We review what is known about the pathogenic mechanisms of va...
Source: Annual Review of Pharmacology and Toxicology - Category: Drugs & Pharmacology Authors: Tags: Annu Rev Pharmacol Toxicol Source Type: research
MRI scans have linked higher blood pressure with greater accumulation of white-matter...Read more on AuntMinnie.comRelated Reading: MRI shows adverse effects of U.S. embassy mystery PET, MRI show physical activity aids brain health Florbetapir-PET links lack of financial acumen to dementia PET, AI show women's brains age differently than men's MRI links lifestyle factors to stroke, dementia risk
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Alzheimer disease and related dementias affect nearly 10% of US adults older than 65 years. With an aging population, the prevalence of dementia is likely to increase, adding to the enormous burden on affected patients, their caregivers, and the health care system. Besides Alzheimer pathology (eg, amyloid and tau protein deposition) in the brain, there is increasing evidence of the contributions of vascular pathology (eg, stroke, subclinical infarct, and ischemic white matter changes) on dementia occurrence. Furthermore, these 2 common pathologies can coexist in individual patients, with evidence that cerebrovascular insul...
Source: JAMA - Category: General Medicine Source Type: research
Possible 30 years life gain per 100 patients and £727m savings Related items fromOnMedica CCGs must focus more on foot care Shocking variation in diabetes care across UK Coronary heart disease remains UK ’s biggest killer The new GP contract: transforming primary care, transforming CVD prevention Dementia and stroke funding remains too low, say experts
Source: OnMedica Latest News - Category: UK Health Source Type: news
Dear Candid Caregiver: My mom passed two years ago and my dad hasn’t done well since. Recently he had a stroke. My sister, who lives 1,000 miles away, came out for mom’s funeral, and she also visited for a few days after dad’s stroke, but she has a job and a family and couldn’t stay long. Now, dad’s been diagnosed with vascular dementia. Realistically, I’m the sole caregiver. I have two teenaged children, a husband who is, so far, supportive, and a job. I’m already beginning to feel burned out after just a few months.  Read the full article on HealthCentral to learn more ...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Photo credit Christian Newman ...My friend can be forgiven for dragging her feet. Her mother has been told often that the brother was ill. It was new information to the mother each time. There was no reason for the daughter to think that the telling of her uncle's death was not going to shock her mother all over again. She seriously thought of not mentioning it. It's not as if a visit was expected. She asked me what I thought. Read the full article on HealthCentral to learn more about how (or if) to tell someone that their spouse or other loved one has died: Carol Bradley Bursack is the Candid Caregiver MedicareFAQ –...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
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