One year in review 2018: Sj ögren's syndrome.

One year in review 2018: Sjögren's syndrome.
Clin Exp Rheumatol. 2018 May-Jun;36 Suppl 112(3):14-26
Authors: Argyropoulou OD, Valentini E, Ferro F, Leone MC, Cafaro G, Bartoloni E, Baldini C
Abstract
Sjögren's syndrome is a complex and potentially disabling slow progressive, systemic disorder. During the last twelve months several original and important contributions have been published on the pathogenesis, diagnosis and therapy of the disease. This review, following the others of this series is aimed at summarising some of the most significant studies that have been recently published. Regarding the pathogenesis, we will specifically focus on novel insights on miRNA, gut microbiota, adaptive and innate autoimmunity and animal models. Concerning novelties in pSS diagnosis, we will focus on salivary gland ultrasonography and histology. Finally, we will conclude with an update of the clinical manifestations of the disease and with an overview of the future therapies.
PMID: 30156536 [PubMed - in process]

Source: Clinical and Experimental Rheumatology - August 31, 2018 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research