Does pain sensitivity increase during ictal period? Evidence from absence epileptic WAG/Rij rats.

CONCLUSION: Our data indicate higher pain sensitivity during the ictal period in absence epilepsy rats. Considering the fact that subjects are less responsive during spike-wave discharges, there is a decrease in the level of consciousness and/or responsiveness ictally during all generalized genetic seizures, this increased pain sensitivity is rather surprising during the ictal period. Although the mechanism remains unknown, this novel finding deserves further investigation. PMID: 30153651 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30153651?dopt=Abstract

Source: Epilepsy and Behaviour - August 25, 2018 Category: Neurology Authors: Velioglu SK, Gedikli O, Yıldırım M, Ayar A Tags: Epilepsy Behav Source Type: research