Immunosuppression-lipid metabolism interplay and medicinal plants in atherosclerosis: a review.

Immunosuppression-lipid metabolism interplay and medicinal plants in atherosclerosis: a review. Curr Pharm Des. 2018 Aug 28;: Authors: Moradi F, Sewell RDE, Lorigooini Z, Rafieian-Kopaei M Abstract Atherosclerosis is a chronic arterial disease responsible for the majority of vascular-related deaths throughout the world. Immune cells and inflammation in conjunction with hyperlipidemia play a key role in atherosclerosis development. Regarding the low efficacy of the synthetic drugs and also the associated negative side effects which can adversely influence health-related quality of life, looking for natural, affordable and non-toxic substances seem necessary. Plant-derived natural products play a critical role in prevention and treatment of atherosclerosis. In this review, we aimed to outline the most important medicinal herbs effective on atherosclerosis through impact on immune system. PMID: 30156151 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research