Increased expression and functionality of the gap junction in peripheral blood lymphocytes is associated with hypertension-mediated inflammation in spontaneously hypertensive rats.

Conclusions: Our data suggest that Cxs may be involved in the regulation of T-lymphocyte homeostasis and the production of cytokines. A clear association was found between alterations in Cxs expression or in Cx43-based GJIC and hypertension-mediated inflammation.
PMID: 30151015 [PubMed - in process]

Source: Cellular and Molecular Biology Letters - August 30, 2018 Category: Biochemistry Authors: Ni X, Li XZ, Fan ZR, Wang A, Zhang HC, Zhang L, Li L, Si JQ, Ma KT Tags: Cell Mol Biol Lett Source Type: research