Efficacy of cariprazine on negative symptoms in patients with acute schizophrenia: A post hoc analysis of pooled data

Although currently approved antipsychotics exert efficacy on positive symptoms of schizophrenia, treatments for negative symptoms remain a major unmet need. Post hoc analyses were used to investigate the possible efficacy of cariprazine in patients with moderate/severe negative symptoms of schizophrenia and no predominance of positive symptoms. Data were pooled from 2 randomized, double-blind, placebo- and active-controlled cariprazine studies in patients with acute schizophrenia (NCT00694707, NCT01104766).

Source: Schizophrenia Research - August 29, 2018 Category: Psychiatry Authors: Willie Earley, Hua Guo, David Daniel, Henry Nasrallah, Suresh Durgam, Yan Zhong, Mehul Patel, Ágota Barabássy, Balázs Szatmári, György Németh Source Type: research