pH stability of human preimplantation embryo culture media: effects of culture and batches

Conclusions: A relevant difference in pH was found between batches of human preimplantation embryo culture media. This suggests that the CO2 level of incubators may need to be adjusted for new batches of culture medium based on measured pH, to anticipate batch variability and safely accommodate limited pH increase over time. This study was unable to identify the cause of the differences in pH between batches, and further investigation on a larger number of batches and other media seems warranted.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research