Neuropathic diabetic foot ulcers treated with cerium dioxide nanoparticles: A case report

Publication date: Available online 29 August 2018Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Nazarii Kobyliak, Ludovico Abenavoli, Liudmyla Kononenko, Dmytro Kyriienko, Mykola SpivakAbstractWound healing in diabetes is frequently impaired and its treatment remains a challenge. The ability of topical application of cerium (Ce) dioxide nanoparticles (CNPs) to accelerate wound healing in an animal model provides a rationale to develop this technology for use in humans affected by traumatic injury, diabetes and burns. We first described a case report of successful topical treatment of neuropathic diabetic foot ulcers with novel gel containing CNPs. The CNPs has bacteriostatic activity, anti-inflammatory properties and can penetrated into the wound tissue and reduced oxidative damage therefore protect regenerative tissue, suggesting a therapeutic potential for topical treatment of diabetic foot ulcers.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research