Ultrastructural changes in microvessels in familial hemiplegic migraine with CACNA1A mutation.
CONCLUSION: The morphological changes described for the first time in FHM1 suggest that the disease may not only be a functional, but also a structural vascular disorder. We suggest that the presence of these vascular abnormalities can interfere with microcirculation causing damage to the cerebral white matter, visible in MRI scans as hyperintense changes.
.
PMID: 30148448 [PubMed - as supplied by publisher]
Source: Clinical Neuropathology - Category: Pathology Authors: Dziewulska D, Kierdaszuk B Tags: Clin Neuropathol Source Type: research
More News: Brain | Genetics | Headache | Migraine | Mitochondria | Neurology | Pathology | PET Scan | Skin | Skin Biopsy