Linking the Heart and the Brain: Neurodevelopmental Disorders In Patients With Catecholaminergic Polymorphic Ventricular Tachycardia

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an uncommon inherited arrhythmia disorder characterized by adrenergically-evoked ventricular arrhythmias. Mutations in the cardiac calcium release channel/ryanodine receptor gene (RYR2) are identified in the majority of patients with CPVT. RyR2 is also the major RyR isoform expressed in the brain.

Source: Heart Rhythm - August 28, 2018 Category: Cardiology Authors: Krystien V.V. Lieve, Judith Verhagen, Jinhong Wei, J. Martijn Bos, Christian van der Werf, Ferran Ros és i Noguer, Grazia M.S. Mancini, Wenting Guo, Ruiwu Wang, Freek van den Heuvel, Ingrid M.E. Frohn-Mulder, Wataru Shimizu, Akihiko Nogami, Hitoshi Horig Source Type: research