Stereotactic body radiation therapy (SBRT) on renal cell carcinoma, an overview of technical aspects, biological rationale and current literature

Stereotactic body radiotherapy (SBRT) is characterized by the delivery of high doses of ionizing radiation in few fractions. It is highly effective in achieving local control, and, due to the high biological effective dose administered, it seems to overcome the radioresistance of renal cell carcinoma (RCC). Thus, SBRT could constitute a treatment option for the management of localized RCC in patients who are not surgical candidates. In this paper, we report an overview about data from the current evidence about SBRT in patients affected by localized RCC.

Source: Critical Reviews in Oncology Hematology - August 28, 2018 Category: Cancer & Oncology Authors: G. Francolini, B. Detti, G. Ingrosso, I. Desideri, C. Becherini, G. Carta, D. Pezzulla, G. Caramia, L. Dominici, V. Maragna, M.A. Teriaca, M. Bottero, L. Livi Source Type: research