A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific, and Temporal Patterns

Price et  al. generate five strains of reporter mice to visualize the expression of individual TLRs on intestinal epithelial cells (IECs). Their findings reveal unexpected diversity in the temporal and spatial patterns of TLR expression and in the responsiveness of IECs to microbial stimuli.

Source: Immunity - August 28, 2018 Category: Allergy & Immunology Authors: April E. Price, Kiarash Shamardani, Kyler A. Lugo, Jacques Deguine, Allison W. Roberts, Bettina L. Lee, Gregory M. Barton Tags: Resource Source Type: research