The effects of Mitochondria-associated long noncoding RNAs in cancer mitochondria: new players in an old arena

LncRNAs, as new players in the old battle against cancer, are significant components of gene regulatory networks. Mitochondria-associated lncRNAs have newly been discovered to work in concert with transcription factors and epigenetic regulators to modulate mitochondrial gene expression and mitochondrial function. Many mitochondria-associated lncRNAs regulate mitochondrial biosynthesis, bioenergetics, apoptosis and possibly govern the cross-talk of mitochondria with nuclei. The complexity of mitochondria-associated lncRNAs is now just starting to envisage.
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research