Urinary sodium excretion has positive correlation with activation of urinary Renin Angiotensin system and reactive oxygen species in hypertensive chronic kidney disease.

In conclusion, high salt intake increases renal renin-angiotensin-system (RAS) activation, primarily, and directly or indirectly affects the production of reactive oxygen species through renal RAS activation.
PMID: 25317016 [PubMed - in process]

Source: J Korean Med Sci - September 1, 2014 Category: Journals (General) Authors: Ahn SY, Kim S, Kim DK, Park JH, Shin SJ, Lee SH, Choi BS, Lim CS, Kim S, Chin HJ Tags: J Korean Med Sci Source Type: research