RPS23RG1 is Required for Synaptic Integrity and Rescues Alzheimer ’s Associated Cognitive Deficits

Although synaptic impairment is prerequisite to cognitive deficiencies in Alzheimer ’s disease (AD), mechanisms underlying the dysregulation of essential synaptic scaffolding components and their integrity remain elusive. RPS23RG1 is a newly identified protein implicated in AD. However, the physiological function of RPS23RG1 has yet to be determined.

Source: Biological Psychiatry - August 24, 2018 Category: Psychiatry Authors: Dongdong Zhao, Jian Meng, Yingjun Zhao, Yuanhui Huo, Yan Liu, Naizhen Zheng, Muxian Zhang, Yue Gao, Zhicai Chen, Hao Sun, Xiangyu Wang, Chuya Jing, Tongmei Zhang, Xian Zhang, Hong Luo, Xin Wang, Jie Zhang, Fa-rong Liu, Yanfang Li, Guojun Bu, Lei Wen, Timo Tags: Priority Communication Source Type: research