Adeno-associated virus 2 mediated gene transfer of vascular endothelial growth factor Trap: a new treatment option for glioma.

CONCLUSION: AAV2-VEGF-Trap has an obvious anti-angiogenic effect and inhibits the growth of glioma just by a single intravenous injection, which is similar to BEV. Moreover, there is a synergistic antitumor effect between AAV2-VEGF-Trap and TMZ.
PMID: 30136881 [PubMed - as supplied by publisher]

Source: Cancer Biology and Therapy - August 23, 2018 Category: Cancer & Oncology Authors: Zhao S, Zhang Y, Wang L, Yang L, Zou L, Gao F Tags: Cancer Biol Ther Source Type: research