Cranial Rhabdomyosarcoma Masquerading as Infectious Mastoiditis: Case Report and Literature Review

Conclusions: Based on abstracted and aggregated information, we identified unique features observed more frequently in each of rhabdomyosarcoma and mastoiditis. These predictive features allow for the differentiation of each diagnosis and avoid the delay of proper treatment.Pediatr Neurosurg
Source: Pediatric Neurosurgery - Category: Neurosurgery Source Type: research

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One of the challenges faced when treating a child with genitourinary rhabdomyosarcoma is what to do when a residual mass remains after organ sparring treatment. The authors present an interesting case which exemplifies the dilemma. The answer to this question is simplified for when the residual mass is associated with pain, is growing or impairs organ function, providing a rational for excision. When this is not the case concern centers around residual disease and recurrence. Today the post-treatment finding of mature rhabdomyoblasts is not a reason for exenterative surgery, however some point bear mentioning.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
Discussion: The incidence of rhabdomyosarcoma arising from endometriosis is exceedingly rare. The accuracy of diagnosing endometriosis and ruling out neoplasm requires coordinated efforts of a multidisciplinary team, involving radiologists, pathologists, oncologists, and gynecologic surgeons. PMID: 31624455 [PubMed - in process]
Source: JSLS : Journal of the Society of Laparoendoscopic Surgeons - Category: Surgery Tags: JSLS Source Type: research
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Conclusions: The proposed nomogram is a reliable and robust tool for accurate prognostic prediction in patients with extremity soft tissue LMS. Introduction Soft tissue leiomyosarcoma (LMS) is an aggressive sarcoma, which originates from smooth muscle cells (1). Soft tissue LMS accounts for about 5–10% of all soft tissue sarcomas (2). It occurs in different sites, including the retroperitoneum, intraabdominal sites, and extremities (3). Extremity LMS comprised about 10–15% of extremity sarcomas, with a preference for the lower limb (4–6). Extremity LMS tends to have a better prognosis than uterine...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 27 March 2019Source: Pathology - Research and PracticeAuthor(s): Yohei Tagami, Shintaro Sugita, Terufumi Kubo, Noriyuki Iesato, Makoto Emori, Kohichi Takada, Mitsuhiro Tsujiwaki, Keiko Segawa, Taro Sugawara, Tomoki Kikuchi, Tadashi HasegawaAbstractA 70-year-old woman developed severe buttock pain that progressed to a walking disturbance. Radiographs and computed tomography scans revealed an osteolytic lesion with osteosclerosis extending from the body to the arch of the fifth lumbar vertebra. Magnetic resonance imaging showed multinodular masses in the fifth lumbar vertebral body extendin...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Abstract A 70-year-old woman developed severe buttock pain that progressed to a walking disturbance. Radiographs and computed tomography scans revealed an osteolytic lesion with osteosclerosis extending from the body to the arch of the fifth lumbar vertebra. Magnetic resonance imaging showed multinodular masses in the fifth lumbar vertebral body extending into the spinous processes and right transverse process. The masses were hypointense to isointense on T1-weighted images and hypointense to hyperintense on T2-weighted images. Histologic examination of biopsy specimens showed destruction of the trabecula of the v...
Source: Pathology, Research and Practice - Category: Pathology Authors: Tags: Pathol Res Pract Source Type: research
Rationale: Rhabdomyosarcoma (RMS) has known as a highly malignant soft tissue sarcoma, representing 5% to 10% of all solid tumors in childhood. Alveolar rhabdomyosarcoma (ARMS) of the retrorectal-presacral space is an extremely rare lesion for adult, no study has been reported in the English literature. Patient concerns: A 51-year-old male presented with abdominal pain for 1 month, significantly worse when having a bowel movement. Diagnosis: Computed tomography (CT) and magnetic resonance imaging (MRI) of the pelvis showed a solid-cystic, enhancing lesion of dimension located in retrorectal-presacral space. The sur...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
ConclusionThe spindle cell embryonal rhabdomyosarcomas is a rare variant of embryonal subtype of RMS, occurring more commonly in children and adolescents. Its less aggressive sarcoma and better prognosis in children or adolescents, establish the correct diagnosis crucial using combination of clinical finding, histopathology and Immunohistochemistry.
Source: Human Pathology: Case Reports - Category: Pathology Source Type: research
It was devastating at the time, but I met amazing people who helped me pursue a career in medical scienceI was 14 years old when I was told I had cancer. It was just before Christmas in 2009 and I ’d had terrible pain in my side for several weeks. After being seen at four different hospitals, I ended up at Birmingham children’s hospital. It was there that I was told I had alveolar rhabdomyosarcoma, words that meant absolutely nothing to me at first. I soon realised they meant cancer.Before my diagnosis, I was far more concerned with schoolwork and my friends – normal things 14-year-olds have to deal with....
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Society Health Cancer Cancer research Medical research Science Careers Education Students Higher education Children NHS Source Type: news
Publication date: August 2018Source: The Journal of Prosthetic Dentistry, Volume 120, Issue 2Author(s): Korbinian Benz, Carla Kozmacs, Andree Piwowarczyk, Jochen JackowskiAbstractA female patient, now aged 17 years, was diagnosed with rhabdomyosarcoma (RMS) in the right pterygopalatine fossa when she was 3 years old. The RMS was successfully treated by excision, but the subsequent radiation and polychemotherapy resulted in the complete anesthesia of the distribution area of the right trigeminal nerve and loss of vision in the right eye. The patient also experienced pain in the mandibular joints and masticatory muscles. Pan...
Source: The Journal of Prosthetic Dentistry - Category: Dentistry Source Type: research
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