EP News: Basic and Translational

Scroll waves are self-organized dynamics of vortex-like rotating waves and form the basis for complex spatiotemporal patterns in excitable systems. Filament-like phase singularities associated with 3-dimensional scroll waves serve as the organizing centers of cardiac arrhythmias. However, one of the main challenges in the field is to directly visualize the 3-dimensional spatiotemporal dynamics of scroll waves inside the heart. Christoph et  al (Nature 2018;555:7698, PMID 29466325) took the advantage of high-resolution 4-dimensional ultrasound-based strain imaging to noninvasively image and quantify the 3-dimensional mechanical scroll waves and filament-like phase singularities in contracting ex vivo models of pig and rabbit hearts.
Source: Heart Rhythm - Category: Cardiology Authors: Tags: EP News Source Type: research