Teenager Keiran Halliday grows 8 inches in a YEAR after brain tumour
Keiran Halliday, 19, from Bridgend, South Wales, has shot up eight inches in the last year after he was diagnosed with acromegaly, where the body produces too much growth hormone.
Condition: Neurological Cancer Intervention: Drug: ASTX727 Sponsors: Massachusetts General Hospital; Astex Pharmaceuticals Not yet recruiting
(Far Eastern Federal University) Scientists from Far Eastern Federal University (FEFU) in cooperation with colleagues from Blokhin Russian Cancer Research Center (Moscow), Switzerland, and Sweden for the first time studied proteins, which constitute WNT signaling pathway of the cancer stem cells of glioblastoma multiforme (GBM CD133+ CSCs), one of the most aggressive brain tumors. Researchers revealed a number of proteins, which are potential targets to attack during complex antitumor therapy. A related article was published in Oncology Reports.
AbstractHere, we report a highly unusual case of high-grade glioneuronal tumor with aneurotrophic tropomyosin receptor kinase (NTRK) fusion gene. A 13-year-old girl presented with headache and vomiting and MRI detected two cystic lesions bilaterally in the frontal areas with surrounding edema. The left larger tumor was removed by left frontal craniotomy. The tumor was diagnosed as a high-grade glioneuronal tumor, unclassified. Methylation profiling classified it as a diffuse leptomeningeal glioneuronal tumor (DLGNT) with low confidence. This tumor showed genotypes frequently found in DLGNT such as 1p/19q codeletion without...
We report two such cases of atypical choroid plexus papilloma in a 5-month-old male child and a 12-year-old female child, where characteristic cytomorphology of CPT was noted in the CSF.
Modern genetic characterization has improved our understanding of prognosis for low-grade glioma (LGG). Although several classic risk factors are known to impact progression free survival (PFS), we sought to identify risk factors in the molecular era. Among patients with LGG who undergo MRI-confirmed gross total resection and initial observation, risk factors for worse PFS include increasing age, increasing tumor size, and IDH-mutant-1p/19q-intact classification. Further study is required to elucidate our findings.
oeder Bernhard H. Rauch The link between thrombocytosis and malignancy has been well known for many years and its associations with worse outcomes have been reported mainly for solid tumors. Besides measuring platelet count, it has become popular to assess platelet function in the context of malignant diseases during the last decade. Malignant gliomas differ tremendously from malignancies outside the central nervous system because they virtually never form distant metastases. This review summarizes the current understanding of the platelet–immune cell communication and its potential role in glioma resistanc...
In the article “Diagnostic performance of an unenhanced MRI exam for tumor follow-up of the optic pathway gliomas in children”, Table 2 data were not presented correctly, with results placed beneath an incorrect heading. Confidence interval also added. The original article has been corrected.
We describe the clinical, electrophysiological, and neuroimaging findings in an adult patient presenting with persistent unilateral abdominal myoclonus configuring an EPC as the evolution of a super-refractory hemibody convulsive status epilepticus, occurred after brain tumor surgery. PMID: 31002150 [PubMed - in process]
Chloe Powell, a 26-year-old midwife from Bristol, developed acromegaly because of a benign brain tumour, which made her hands and feet grow uncontrollably, and her facial features swell up.
Cancers, Vol. 9, Pages 103: Secondary Intracranial Tumors Following Radiotherapy for Pituitary Adenomas: A Systematic Review Cancers doi: 10.3390/cancers9080103 Authors: Ryuya Yamanaka Eisuke Abe Toshiteru Sato Azusa Hayano Yasuo Takashima Pituitary adenomas are often treated with radiotherapy for the management of tumor progression or recurrence. Despite the improvement in cure rates, patients treated by radiotherapy are at risk of development of secondary malignancies. We conducted a comprehensive literature review of the secondary intracranial tumors that occurred following radiotherapy to pituitary aden...