Effect of Optimized Concentrations of Basic Fibroblast Growth Factor and Epidermal Growth Factor on Proliferation of Fibroblasts and Expression of Collagen: Related to Pelvic Floor Tissue Regeneration.
Conclusions: The optimal concentration of both bFGF and EGF to promote cell proliferation and collagen expression in fibroblasts was 10 ng/ml at which fibroblasts grew faster and secreted more Type I and III collagens into the extracellular matrix, which might contribute to the stability of the pelvic floor microenvironment.
PMID: 30127219 [PubMed - in process]
Source: Chinese Medical Journal - Category: General Medicine Authors: Jia YY, Zhou JY, Chang Y, An F, Li XW, Xu XY, Sun XL, Xiong CY, Wang JL Tags: Chin Med J (Engl) Source Type: research