Endometriosis , infertility, laparoscopic surgery and IVF.

Endometriosis is a very common finding in infertile women and is one of the most controversial topics. This is true for multiple reasons. For example, lots of patients with endometriosis have no symptoms at all, and this is an incidental finding either on a vaginal ultrasound scan, which picks up a chocolate cyst, or on a diagnostic laparoscopy done for checking infertility. Now, on an ultrasound scan or a laparoscopy, once the diagnosis is made, then doctors usually get itchy fingers and want to treat it. The treatment is usually doing an operative laparoscopy to remove the lesion, but whether this actually helps the patient is very controversial and the worry of causes that may actually reduce fertility because every time you remove normal ovarian tissue as well, whenever you're removing the endometriotic cyst.Of course once the laparoscope is  already inside, most surgeons will go ahead and do the procedure anyway, but this is not always in the patient's best interest, especially for an asymptomatic patient where this is an incidental finding. Also, the treatment which is offered to the patient, to a large extent, depends on who makes the diagnosis of endometriosis 'cause if it's a gynecologist who does endoscopic surgery, then usually this is what the treatment will be offered because if you have a hammer in your hand, you look for nails. If, on the other hand, the diagnosis is made by an IVF specialist, then the patient is usually advised IVF, and that's why patient...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs

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Publication date: January 2020Source: Biometric Technology Today, Volume 2020, Issue 1Author(s): US NIST (the National Institute of Standards and Technology) has released three new biometric databases – featuring fingerprints, facial photographs and iris scans – designed to help researchers reduce the error rates of biometric systems.
Source: Biometric Technology Today - Category: Information Technology Source Type: research
Publication date: January 2020Source: Biometric Technology Today, Volume 2020, Issue 1Author(s): Jason TooleyThe use of biometrics by police forces has rarely been out of the headlines over the past year. As with many emerging technologies, it has hit significant hurdles. Recently in an unprecedented move, the UK's Information Commissioner's Office (ICO) – the government body responsible for GDPR and data privacy enforcement – launched an independent investigation into the use of facial recognition at London's King's Cross train station, after it was revealed that the general public were having their faces scan...
Source: Biometric Technology Today - Category: Information Technology Source Type: research
Conclusion Anlotinib effectively controlled the growth of NSCLC and improved TAO related symptoms. Anlotinib maybe normalize disordered growth of blood vessels through the VEGF signaling pathway, rather than simply inhibiting angiogenesis. 
 DOI: 10.3779/j.issn.1009-3419.2020.01.10
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research
Ureaplasma urealyticum (uu) is one of the most common agents of urogenital infections and is associated with complications such as infertility, spontaneous abortion and other sexually transmitted diseases. Here, a DNA sensor based on oligonucleotide target-specific gold nanoparticles (AuNPs) was developed, in which the dispersed and aggregated states of oligonucleotide-functionalised AuNPs were optimised for the colorimetric detection of a polymerase chain reaction (PCR) amplicon of U. urealyticum DNA. A non-cross-linking approach utilising a single Au-nanoprobe specific of the urease gene was utilised and the effect of a ...
Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research
In this research, the hydrothermal method was used for synthesising cellulose acetate (CA) templated nanorods like CuS fibres using vegetable extract (Brassica oleracea var. italica). These extracts act as a reducing agent in the presence of CA. Surprisingly, when the same reaction was carried out in the absence of CA and broccoli extract, structural morphology disappeared and was found as agglomerated. In the presence of cellulose templated extract mediated CuS has revealed as nanorods like fibres and was confirmed by field emission scanning electron microscope analysis. Their crystallinity property of CuS nanoparticles (...
Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research
To sustained release of an anticancer drug, oxaliplatin (OX), a non-toxic and biocompatible nanocarrier based on bovine serum albumin (BSA) were synthesised by desolvation method and characterised using Fourier-transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), atomic force microscopy (AFM) and dynamic light scattering. The results showed that the BSA nanoparticles (BSANPs) with a mean magnitude of 187.9 ± 1.2 nm have spherical morphology with a smooth surface and a uniform distribution. Furthermore, OX was loaded onto the BSANPs and the loading was confirmed...
Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research
Publication date: Available online 15 January 2020Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Anna Xu, Bart Larsen, Erica B. Baller, J. Cobb Scott, Vaishnavi Sharma, Azeez Adebimpe, Allan I. Basbaum, Robert H. Dworkin, Robert R. Edwards, Clifford J. Woolf, Simon B. Eickhoff, Claudia R. Eickhoff, Theodore D. SatterthwaiteAbstractCharacterizing a reliable, pain-related neural signature is critical for translational applications. Many prior fMRI studies have examined acute nociceptive pain-related brain activation in healthy participants. However, synthesizing these data to identify convergent patterns of activa...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Publication date: Available online 15 January 2020Source: Journal of Molecular StructureAuthor(s): J. Mobika, M. Rajkumar, V. Nithya Priya, S.P. Linto SibiAbstractNano-biocomposites that mimics bone’s extracellular matrix with hydroxyapatite as an inorganic and silk fibroin as organic phase for three different ratios via a simple in-situ co-precipitation method have been synthesized. The silk fibroin, a biodegradable polymer from cocoons of Bombyx mori silkworm were extracted by employing a chemical-free High-Temperature High-Pressure method as a degumming route. Then followed by the regeneration process which was do...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 15 January 2020Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Susmita Biswas, Udita Chatterjee, Sriparnika Sarkar, Finaz Khan, Debbethi Bera, Madhumita Mukhopadhyay, Soumyabrata Goswami, Sandip Chakrabarti, Susmita DasAbstractLow Molecular Weight (LMWG) gelators are small molecules that form supramolecular self-assembly involving physical forces and are highly biocompatible. However, fragility of these physical gels restricts their applicability where gels of higher mechanical strength are required. Herein, we have developed two different types of 2-D carbon nanomaterials viz. g...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Publication date: Available online 15 January 2020Source: Biochimica et Biophysica Acta (BBA) - BiomembranesAuthor(s): Gopal Pandit, Karishma Biswas, Suvankar Ghosh, Swapna Debnath, Anil P. Bidkar, Priyadarshi Satpati, Anirban Bhunia, Sunanda ChatterjeeAbstractThe widespread abuse of antibiotics has led to the use of antimicrobial peptides (AMPs) as a replacement for the existing conventional therapeutic agents for combating microbial infections. The broad-spectrum activity and the resilient nature of AMPs has mainly aggrandized their utilization. Here, we report the design of non-toxic, non-hemolytic and salt tolerant und...
Source: Biochimica et Biophysica Acta (BBA) Biomembranes - Category: Biochemistry Source Type: research
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