People Are Now Taking Placebo Pills to Deal With Their Health Problems —And It’s Working

For over 20 years, Linda Buonanno lived in fear that her irritable bowel syndrome (IBS) would suddenly interrupt her daily routine with frequent trips to the bathroom and unbearable cramping. Buonanno, now a 71-year-old medical assistant and hairdresser from Methuen, Mass., tried everything from drugs to dairy-free diets. Nothing worked. She remembers a particularly tough period over 10 years ago, when she was working on the factory floor of a medical-device company for up to 10 hours a day, six days a week. When an IBS episode would strike, her co-workers would cover for her as she huddled in a corner, keeled over in pain. If she wanted to go dancing with friends at the local club on Sunday, Buonanno would stop eating on Friday so there wouldn’t be anything in her system to interrupt her plans. “It was a horrible way to live,” she says. One day in 2009, she saw a TV ad looking for people with IBS to enroll in a study. She signed up and was thrilled when she was among about 80 people selected to take part in a first-of-its-kind clinical trial. But when she found out what kind of treatment she’d be receiving, Buonanno felt deflated: a placebo pill. The doctors told her there were no active ingredients in the pills, and the word placebo was labeled clearly on the bottle. She felt she’d gotten her hopes up for nothing. Three weeks later, after taking the pill twice daily, Buonanno was symptom-free. She had never gone so long without an attack. &ldq...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized medicine Research Source Type: news

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Antonio Macci ò, Silvia Busquets, Clelia Madeddu, Josep M. Argilés
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Nikitas N. Nomikos, Pantelis T. Nikolaidis, Caio V. Sousa, Apostolos E. Papalois, Thomas Rosemann, Beat Knechtle
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Authors: Panhwar MS, Li J, Zidar DA, Clevenger J, Lipinski J, Patel TR, Karim A, Saric P, Patel SM, Kalra A, Attizzani G Abstract OBJECTIVES: To investigate the effect of TAVR technique on in-hospital and 30-day outcomes in patients with aortic stenosis (AS) and reduced ejection fraction (EF). BACKGROUND: Patients with AS and concomitant low EF may be at risk for adverse hemodynamic effects from general anesthesia utilized in transcatheter aortic valve replacement (TAVR) via the conventional strategy (CS). These patients may be better suited for the minimally invasive strategy (MIS), which employs conscious sed...
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
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Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
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Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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Source: Redox Biology - Category: Biology Source Type: research
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Source: Mammalian Biology - Category: Biology Source Type: research
Authors: Shin HJ, Lee H, Na HS Abstract Background: Irrigation fluid absorption during endoscopic surgery has been known to alter blood coagulation. We investigated the effect of an irrigation fluid on the coagulation according to the hemodilution level using rotational thromboelastometry (ROTEM) tests. Methods: Venous blood was taken from 12 healthy volunteers and divided into four specimen bottles, which were diluted to different levels (0%, 10%, 20%, and 40%) using a mixture of 2.7% sorbitol-0.54% mannitol solution. Then, ROTEM analysis was performed. Results: Significant prolongation of clotting time (C...
Source: Korean Journal of Anesthesiology - Category: Anesthesiology Tags: Korean J Anesthesiol Source Type: research
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Source: Korean Journal of Anesthesiology - Category: Anesthesiology Tags: Korean J Anesthesiol Source Type: research
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