Association between typical electrocardiographic abnormalities and NT-proBNP elevation in a large cohort of patients with Chagas disease from endemic area

Chagas cardiomyopathy is the most harmful complication of Chagas disease. The electrocardiogram is a well-studied exam and has been considered an important tool for detection and evaluation of Chagas cardiomyopathy since the first years of its description. Many of its abnormalities have been described as associated with a worse prognosis. Serum BNP levels were described as inversely related to the left ventricular ejection fraction and as an independent predictor of death. It was not reported how electrocardiographic alterations correlate to NT-proBNP and its analog.

Source: Journal of Electrocardiology - August 22, 2018 Category: Cardiology Authors: Bruno Oliveira de Figueiredo Brito, Marcelo Martins Pinto Filho, Clareci Silva Cardoso, Claudia Di Lorenzo Oliveira, Ariela Mota Ferreira, Lea Campos de Oliveira, Paulo Gomes, Maria do Carmo Pereira Nunes, Ester Cerdeira Sabino, Antonio Luiz Pinho Ribeiro Source Type: research