Beneficial Effects of Lifestyle intervention in non-obese patients with non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease and is one of the leading causes of end-stage liver disease and hepatocellular carcinoma worldwide [1,2]. Although NAFLD is strongly associated with metabolic syndrome and obesity [3], around 10-20% of NAFLD patients have relatively normal body mass index (BMI), a condition often described as non-obese or lean NAFLD [4]. Studies based on liver histology or non-invasive tests of fibrosis suggest that these non-obese patients may also harbor non-alcoholic steatohepatitis (NASH) and advanced fibrosis [5 –8].

Source: Journal of Hepatology - August 22, 2018 Category: Gastroenterology Authors: Vincent Wai-Sun Wong, Grace Lai-Hung Wong, Ruth Suk-Mei Chan, Sally She-Ting Shu, Bernice Ho-Ki Cheung, Liz Sin Li, Angel Mei-Ling Chim, Carmen Ka-Man Chan, Julie Ka-Yu Leung, Winnie Chiu-Wing Chu, Jean Woo, Henry Lik-Yuen Chan Source Type: research