Pseudo-Renal Tubular Acidosis: Conditions Mimicking Renal Tubular Acidosis

Publication date: July 2018Source: Advances in Chronic Kidney Disease, Volume 25, Issue 4Author(s): Junior Uduman, Jerry YeeHyperchloremic metabolic acidosis, particularly renal tubular acidosis, can pose diagnostic challenges. The laboratory phenotype of a low total carbon dioxide content, normal anion gap, and hyperchloremia may be misconstrued as hypobicarbonatemia from renal tubular acidosis. Several disorders can mimic renal tubular acidosis, and these must be appropriately diagnosed to prevent inadvertent and inappropriate application of alkali therapy. Key physiologic principles and limitations in the assessment of renal acid handling that can pose diagnostic challenges are enumerated.
Source: Advances in Chronic Kidney Disease - Category: Urology & Nephrology Source Type: research