The age-calibrated measured glomerular filtration  rate improves living kidney donation selection process

Recommendations on the glomerular filtration rate (GFR) threshold compatible with living kidney donation are not agreed upon. The recent KDIGO guidelines suggested a reset of the conventional cutoff value of 80 to 90 mL/min/1.73 m2. While GFR physiologically declines with age, it is unclear whether and how age should be taken into account for selecting acceptable pre-donation GFR. In this multicenter retrospective study encompassing 2007 kidney donors in France, we evaluated the impact of age using two threshold measured GFR (mGFR)s (80 and 90 mL/min/1.73 m2).

Source: Kidney International - August 21, 2018 Category: Urology & Nephrology Authors: Fran çois Gaillard, Marie Courbebaisse, Nassim Kamar, Lionel Rostaing, Arnaud Del Bello, Sophie Girerd, Michèle Kessler, Martin Flamant, Emmanuelle Vidal-Petiot, Marie-Noelle Peraldi, Lionel Couzi, Pierre Merville, Paolo Malvezzi, Benedicte Janbon, Brun Tags: Clinical Investigation Source Type: research