Loureirin B inhibits the proliferation of hepatic stellate cells and the Wnt/ β-catenin signaling pathway by regulating miR-148-3p.

Conclusion: Our results suggest that loureirin B inhibited the proliferation and promoted the apoptosis of HSCs, and suppressed the Wnt/β-catenin signaling pathway via regulation of miR-148-3p.
PMID: 30123297 [PubMed - in process]

Source: Cellular and Molecular Biology Letters - August 21, 2018 Category: Biochemistry Authors: Hu JP, Zhang R, Tang M, Li YL, Xun LT, Shi ZZ, An Y, Li T, Song ZJ Tags: Cell Mol Biol Lett Source Type: research