Subretinal macrophages produce classical complement activator C1q leading to the progression of focal retinal degeneration

The role of the alternative complement pathway and its mediation by retinal microglia and macrophages, is well-established in the pathogenesis of Age-Related Macular Degeneration (AMD). However, the contributi...

Source: Molecular Neurodegeneration - August 20, 2018 Category: Neurology Authors: Haihan Jiao, Matt Rutar, Nilisha Fernando, Ted Yednock, Sethu Sankaranarayanan, Riemke Aggio-Bruce, Jan Provis and Riccardo Natoli Tags: Research article Source Type: research